Who We Are
At our core is perseverance–a fierce determination to overcome any obstacle, regardless of setbacks, on behalf of patients, caregivers, and their loved ones. We will not be bound by doing what’s been done before. Instead, we free ourselves from preconceived notions to discover solutions that advance patient care. Our mission is clear. Otsuka-people: creating new products for better health worldwide.
If you think this is impossible,
you've never met an Otsuka-person.
Model portrayal.
© 2025 Otsuka America Pharmaceutical, Inc. All rights reserved.
Our Focus
Neuroscience
Our driving philosophy at Otsuka is to serve those with unmet medical needs, and that couldn’t be more true than in our dedication to the central nervous system (CNS) space. In our 30 years of experience working in this therapeutic area, we continue to innovate and defy limitation by taking risks to overcome the complexities of treating mental health. We respect the value within every mind and are committed to making a difference in the lives of patients living with schizophrenia, major depressive disorder, bipolar disorder, anxiety disorders, and other CNS conditions.
Nephrology & Immunology
Recognizing the complexity of kidney and immune-mediated diseases and the critical gaps in research and clinical expertise, Otsuka remains committed to pioneering advancements. Building on decades of nephrology breakthroughs, we have expanded our focus to immune-mediated kidney diseases to address significant unmet needs. Our dedication to innovation continues to drive the development of groundbreaking therapeutics, transforming treatment possibilities.
Discover our pipeline.
Our Legacy
1921
Busaburo Otsuka founded Otsuka in Tokushima Prefecture, Japan, with an unconventional idea and the belief that anything is possible. Otsuka has been on a journey of creativity and innovation ever since.
1985
The first Otsuka US research and development base was established in Rockville, Maryland. Just a few years later, in 1989, Otsuka’s first US commercial organization was created, Otsuka America Pharmaceutical, Inc (OAPI).
2002
Otsuka’s second US location, in Princeton, New Jersey, was opened. We continued our evolution, and in 2007 Otsuka Pharmaceutical Development & Commercialization, Inc (OPDC), was created to oversee all commercial pharmaceutical and medical device activities in the United States.
2020
Today the two companies, OAPI and OPDC, are part of one family—the Otsuka Holdings Co, Ltd, that has over 180 companies, with more than 45,000 employees in 28 countries around the world.
Discover our latest milestones and future plans in the 2023-2024 Economic and Health Impact Report.
Our Family of Companies
Our family of companies is committed to offering innovative products that go beyond healthcare to improve the health and well-being of patients. Otsuka America Pharmaceutical, Inc (OAPI) and Otsuka Pharmaceutical Development & Commercialization, Inc (OPDC) belong to a distinguished family of US affiliates.